In fact, it can be considered a prodrug in most aspects of the term because it only comes into effect after metabolism by the body needs to be broken down first before it becomes active. Vyvanse (Lisdexamfetamine)is widely documented as an effective drug among children and adults alike for the treatment of ADHD so its application towards BED just seals the aspect of versatility. This article totally educates one on the usages, advantages, danger, and many more features of Vyvanse (Lisdexamfetamine) in a way that will make it easier for patients and their caregivers to understand the medicine.
What is Vyvanse (Lisdexamfetamine)?
Although most of the ADHD medications fall under the class of amphetamine group, one particularly important thing regarding Vyvanse (Lisdexamfetamine) is that it itself is an inactive drug until and unless it gets metabolized by the body into dextroamphetamine, which is the active form.
How Does Vyvanse (Lisdexamfetamine)Work?
This property of Vyvanse (Lisdexamfetamine) results in some relative benefits compared with the other drugs in its class that would suggest a less severe time to onset of action, lower potential for abuse, and greater duration of action. The active metabolite form of Vyvanse (Lisdexamfetamine) enhances both attentional and impulse control deficits in patients with ADHD, as well as binge eating episodes in patients with binge eating disorder and transplantations.
Medicine mostly works on neurochemicals that live in the brain. These neurotransmitters play a great deal of importance to attention, hyperactivity, and impulse control. It is hypothesized these neurotransmitters, being deficient when they are, are associated with obvious hyperactivity, impulsivity, and inattention symptoms with ADHD.
When administrated orally, it gets metabolized inside the body into dextroamphetamine within that time of dopamine and norepinephrine surge in the brain. It develops a sense of concentration, reduces impulsive behavior events, and evolves the cognitive function even better. This medicine has been developed very specially because this medicine gets metabolized very slowly. The active component stays released and continues the effect for almost 10-12 hours of a complete day. It is a medicine like Ciprofloxacin (Cipro).
For binge eating disorder, it has been hypothesized that Vyvanse (Lisdexamfetamine) reduces impulses for the episodes of binge eating because it also acts through the same pathways. This mechanism is not confirmed, but it was hypothesized that this elevation of dopamine and norepinephrine levels acts by modulating the reward circuit and impulsivity, which are the most important sites of pathology in BED and diagnosed
Vyvanse (Lisdexamfetamine) Approved Indications
Millions around the globe have this disease under neurodevelopmental disorder. This illness demonstrates symptoms including Failure to give sustained attention more than a fleeting period; Hyperactivity; Impulsiveness. Such a condition implies an impairment in a couple of sections within the affected field of their lives like work or schoolwork and social ones.
Vyvanse (Lisdexamfetamine) resulted in an increase of attention and reduction of symptoms of impulsivity and hyperactivity among ADHD subjects. It is long-acting; thus, this drug will be appropriate for patients that would need to have their symptoms controlled all day long and not be required to have multiple doses each day.
BED is intended to be the most prevalent form of the eating disorder in America that will have the worst impact on a patient’s physiological and psychic well-being.
VYVANSE decreased binge eating episodes of BED-patients, enabling better regulation of food-related activity and more efficiently with fewer undesirable emotional after-effects of the disease.
Benefits of Vyvanse (Lisdexamfetamine)
1. Long acting
The duration of action is associated with the main advantage of Vyvanse (Lisdexamfetamine). One dose takes 12 hours of action. Such a long effect allows maintaining attention and control for most of the day without one or several daily administrations and is immensely helpful for school-aged children or adults having to do complicated workday-in and day-out.
This is less susceptible to abuse.
Vyvanse is a prodrug-it must be metabolized by the body to have an actual effect. The slow rate at which this drug converts in the system lowers the chances of abuse than other stimulant drugs; however, because it is abused either by crushing or snorting, this formulation makes Vyvanse an infinitely safer medicine for people who might be prone to substance abuse.
2. Efficacious for Binge Eating Disorder Treatment
Vyvanse is the first approved and only prescription medicine by the FDA, which is put into action in adults to treat moderate to-severe binge eating disorder. The decrease in the frequency of bingeing episodes has been shown to be an effective solution for patients experiencing such a difficult condition.
3. Better Quality of Life
Life for an ADHD patient would be good, especially through influence on quality of life through improvement in attention, concentration, and other impulse control means. All this would be interpreted into academic and workplace performance as well as to more meaningful relationships besides overall well-being. For a BED patient, Vyvanse would help reduce binge eating episodes and therefore improve emotional wellbeing with much healthier relationships toward food.
Side Effects and Risk Factor of (Lisdexamfetamine)
Like any other medication, Vyvanse has side effects and risk factors. Most patients tolerate the drug, while other patients develop them.
Common Side Effects
· Mouth dryness
· Bad appetite
· Weight loss
· Sleeplessness
· Fast heartbeats
· Anxiety
· Mood swing
· Nausea
All side effects are mild and will resolve if treatment is continued. Discuss these with your prescriber if they persist or are particularly troublesome.
1. Serious Adverse Reactions
Cardiovascular complications: This drug might predispose a patient to an increased heart rate and high blood pressure, thus predisposing them to risks in the presence of such pre-existing cardiac complications. The patients, therefore, should be followed up closely concerning cardiovascular complications while on Vyvanse.
The psychiatric effects include development or deterioration of psychiatric symptoms which can be anxiety, agitation, and hallucination in patients. Patients with a psychiatric history should therefore be carefully followed while on Vyvanse.
Growth Retardation in Pediatrics: Growth retardation would quite certainly be there in children who are on a stimulant, such as Vyvanse. The child’s height would be taken frequently, and weight obtained on paper to have it marked so proper growth could be noted and watched.
2. Interaction with other medicines:
Contraindications:
To whom is this drug not advisable? Vyvanse is not advisable to all. Vyvanse strictly is not advisable to a patient who has some past record of abuse of drugs or alcohol. Cardiovascular conditions like hypertension or ischemic heart disease Hyperthyroidism Glaucoma Patients who are suffering from suicidal and homicidal tendencies Patients under treatment of MAOIs
Before prescribing any medicine with Vyvanse, he needs to know the entire history of the patient. Only when that occurs can he decide whether it is incredibly helpful for the patient or not.
Vyvanse (Lisdexamfetamine) in Daily Life: Dosage and Uses
The medication comes in two forms. There are capsules and chewable tablets. The oral pill tablet dosages start from 10 mg (about the weight of a grain of table salt) and go up to 70 mg (about twice the weight of a grain of rice). One should not take medicine in the afternoon or late at night because it causes sleeplessness.
Therefore, it should provide a safe space to store Vyvanse because it is a Schedule II controlled substance with a high potential for abuse. Additionally, the patient should not have any other prescription drugs and this Vyvanse-only must be taken by the patient only.
Conclusion
Indeed, an extraordinarily strong drug, which is even prescribed for ADHD and binge eating disorder. It has a long duration of action; it also has low abuse potential. Indeed, it is highly effective in treating both disorders, hence the huge demand both from the patients and the clinicians. But, like all prescription medicines, it is always best to weigh an advantage against some sort of risk and side effect.
Even the focus, attention, and impulse control of an individual suffering from ADHD may even become better when one takes Vyvanse to that extent. In the case of binge eating disorder too, the medicine would effectively treat this condition and minimize the binge-eating episodes coupled with enhancing emotional well-being. The same patients, however, should be in close contact with the physician so they can tell if Vyvanse is needed for their needs and be careful of the side effects and adverse effects of the drug.
